Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 18/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8308941 | 0.99 | BRS3 (0.58) | BRS3AOC3SCN2ASCN10A | |
| SCHEMBL8112598 | 0.90 | BRS3 (0.59) | BRS3SCN2ASCN10A | |
| SCHEMBL8305740 | 0.85 | BRS3 (0.59) | BRS3 | |
| Hydrochloric Acid SCHEMBL8572447 | 0.84 | BRS3 (0.58) | BRS3 | |
| SCHEMBL8107240 | 0.83 | BRS3 (0.62) | BRS3 | |
| SCHEMBL8110713 | 0.83 | BRS3 (0.57) | BRS3 | |
| SCHEMBL8112630 | 0.83 | BRS3 (0.55) | BRS3 | |
| SCHEMBL8112556 | 0.82 | BRS3 (0.55) | BRS3 | |
| Hydrochloric Acid SCHEMBL8304300 | 0.82 | BRS3 (0.56) | BRS3 | |
| Hydrochloric Acid SCHEMBL8309307 | 0.82 | BRS3 (0.54) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986302-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | claimed |
| WO-1998054966-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | claimed |
| EP-0986302-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0891333-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998054966-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |
| WO-1997036875-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |