Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 3/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853265 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL15959591 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL19242663 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL9006 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL12689155 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL2857459 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL6376667 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL4969252 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL15814770 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA | |
| SCHEMBL8522586 | 0.84 | MEN1 (0.51) | MEN1KMT2APYGBGBA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034080-A | ALZHEIMER'S DISEASE | QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| EP-0804163-A1 | IMPROVED METHOD FOR STABILIZATION OF BIOLOGICAL SUBSTANCES DURING DRYING AND SUBSEQUENT STORAGE AND COMPOSITIONS THEREOF | QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |
| EP-0755249-A1 | USE OF MAILLARD REACTION INHIBITORS FOR THE TREATMENT OF AMYLOIDOSIS-BASED DISEASE | QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996005809-A1 | IMPROVED METHOD FOR STABILIZATION OF BIOLOGICAL SUBSTANCES DURING DRYING AND SUBSEQUENT STORAGE AND COMPOSITIONS THEREOF | QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) | 1996-02-29 | — | — | WO | disclosed |
| WO-1995028151-A1 | USE OF MAILLARD REACTION INHIBITORS FOR THE TREATMENT OF AMYLOIDOSIS-BASED DISEASE | QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) | 1995-10-26 | — | — | WO | disclosed |