SCHEMBL8105570

SCHEMBL8105570

CCCCCCCCCCCCCCCc1cccc(OC(CC)C([NH])=O)c1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 9/20 0.59
PPARG P37231 5/20 0.59
PTGDR2 Q9Y5Y4 1/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
HDAC1 Q13547 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9436001 1.00 PPARA (0.59) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL77120 0.91 PPARA (0.57) PPARAPPARGCNR1CNR2LPL
SCHEMBL4808774 0.90 PPARA (0.59) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL4810429 0.88 PPARA (0.64) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL6667450 0.87 PPARA (0.59) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL9436008 0.87 PPARA (0.59) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL9128083 0.84 PPARA (0.48) PPARAPPARGPTGDR2CNR1CNR2
SCHEMBL10378308 0.83 PLA2G4B (0.54)
SCHEMBL13054393 0.83 PPARA (0.54) PPARAPPARGCNR1CNR2HDAC1
SCHEMBL646705 0.82 PPARA (0.66) PPARAPPARGCNR1CNR2LPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US claimed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US claimed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US claimed
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
EP-0651289-B1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
EP-0329088-B1 Processing method and bleaching solution for silver halide color photographic light-sensitive materials KONISHIROKU PHOTO IND (JP) 1997-04-23 EP disclosed
EP-0646840-B1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK CO (US) 1997-01-29 EP disclosed
US-5591569-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1997-01-07 US disclosed
US-5561040-A SILVER HALIDE COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1996-10-01 US disclosed
US-4293691-A Method for preparing magenta couplers having thioether groups FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4221860-A COLOR REVERSAL, DEVELOPMENT WITH COMPETING COUPLER, EMULSION CONTAINING BLUE-SENSITIVE METHYLENE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US disclosed
US-4106942-A COMPOUNDS CONTAINING SULFIDE, KETONE, AND AMIDE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1978-08-15 US disclosed
US-4029508-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-06-14 US disclosed
US-4022620-A SILVER HALIDE, AMINE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-10 US disclosed
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US disclosed
US-3990896-A YELLOW COLOR FORMING COUPLERS WITH 5-ALKYLIDINE-3-HYDANTOINYL GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1976-11-09 US disclosed