Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.65 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118703 | 0.94 | TBXA2R (0.66) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8105316 | 0.91 | TBXA2R (0.65) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8120904 | 0.90 | TBXA2R (0.61) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8113863 | 0.88 | TBXA2R (0.59) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL7221042 | 0.88 | TBXA2R (0.61) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL9252158 | 0.88 | TBXA2R (0.82) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8120072 | 0.87 | TBXA2R (0.60) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8120060 | 0.87 | TBXA2R (0.62) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8114147 | 0.86 | TBXA2R (0.68) | TBXA2RTBXAS1HDAC8 | |
| SCHEMBL8123623 | 0.86 | TBXA2R (0.65) | TBXA2RTBXAS1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-6013667-A | Benzenesulfonylamine compounds, process for preparing them and pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |