Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103895 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL8105892 | 0.82 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL9093624 | 0.82 | HTR1B (0.66) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL22439633 | 0.82 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL8820614 | 0.79 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL6626131 | 0.78 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL6793289 | 0.78 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL6087082 | 0.77 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL16801495 | 0.77 | KDM4E (0.65) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 | |
| SCHEMBL18324775 | 0.77 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |