Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.43 |
| ▸ | FNTA | P49354 | 4/20 | 0.43 |
| ▸ | FNTB | P49356 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8309405 | 0.99 | BRS3 (0.45) | BRS3PGGT1BFNTAFNTBTRPA1 | |
| SCHEMBL7453578 | 0.91 | BRS3 (0.43) | BRS3PGGT1BFNTAFNTBCTSS | |
| SCHEMBL8097324 | 0.85 | BRS3 (0.48) | BRS3CTSSGRIN1GRIN2BKCNH2 | |
| Hydrochloric Acid SCHEMBL8306295 | 0.84 | BRS3 (0.47) | BRS3CTSSGRIN1GRIN2BKCNH2 | |
| SCHEMBL8107069 | 0.82 | BRS3 (0.51) | BRS3GRIN1GRIN2BKDM1A | |
| SCHEMBL7919393 | 0.81 | BRS3 (0.62) | BRS3GRIN1GRIN2B | |
| SCHEMBL8097365 | 0.81 | BRS3 (0.50) | BRS3PGGT1BFNTAFNTBMAOB | |
| SCHEMBL7921269 | 0.81 | BRS3 (0.56) | BRS3TRPA1PDE4BGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL8521500 | 0.80 | BRS3 (0.61) | BRS3GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL8305721 | 0.80 | BRS3 (0.49) | BRS3PGGT1BFNTAFNTBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986302-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | claimed |
| WO-1998054966-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | claimed |
| EP-0891333-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036875-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |