Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 8/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108361 | 0.91 | ABCB1 (0.34) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL8112409 | 0.91 | ABCB1 (0.34) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL8108567 | 0.86 | ABCB1 (0.34) | ABCB1NR1H2 | |
| SCHEMBL9595613 | 0.86 | ABCB1 (0.34) | ABCB1NR1H2 | |
| SCHEMBL8112383 | 0.85 | ABCB1 (0.32) | ABCB1PIK3CD | |
| SCHEMBL2080032 | 0.85 | SRC (0.35) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL8107847 | 0.85 | SRC (0.35) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL9595521 | 0.84 | ABCB1 (0.34) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL8112273 | 0.83 | SRC (0.34) | ABCB1NR1H2SRCMEN1KMT2A | |
| SCHEMBL12431668 | 0.83 | NR1H2 (0.37) | ABCB1NR1H2SRCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |