SCHEMBL8106696

SCHEMBL8106696

COc1nn(C)c(=O)n1-c1ccsc1CON=C(C)c1cccc([Si](C)(C)C)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8106692 1.00 PPARG (0.30) PPARGPPARA
SCHEMBL8100200 0.87 KMT2A (0.36) PPARGPPARA
SCHEMBL8098283 0.87 KMT2A (0.36) PPARGPPARA
SCHEMBL8104333 0.83 PPARG (0.31) PPARGPPARA
SCHEMBL8104329 0.83 PPARG (0.31) PPARGPPARA
SCHEMBL8552569 0.74 MAPT (0.36) PPARGPPARA
SCHEMBL8552570 0.74 MAPT (0.36) PPARGPPARA
SCHEMBL7006649 0.73 KMT2A (0.36) PPARGPPARA
SCHEMBL8310893 0.73 PPARG (0.31) PPARGPPARA
SCHEMBL119998 0.73 KMT2A (0.37) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096895-A Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-08-01 US claimed
EP-0825992-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-04 EP claimed
WO-1996036633-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-11-21 WO claimed
US-6096895-A Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-08-01 US disclosed