Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.60 |
| ▸ | FNTB | P49356 | 16/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501264 | 1.00 | FNTA (0.60) | FNTAFNTBPGGT1BPARP1PARP2 | |
| Trifluoroacetic Acid SCHEMBL8455766 | 0.96 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL3501071 | 0.93 | FNTA (0.61) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL7912668 | 0.92 | FNTA (0.60) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL3501187 | 0.92 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL3502717 | 0.92 | FNTA (0.60) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL8121176 | 0.92 | FNTA (0.60) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL3499566 | 0.92 | FNTA (0.60) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL3499735 | 0.92 | FNTA (0.58) | FNTAFNTBPGGT1BALDH1A1LMNA | |
| SCHEMBL3499844 | 0.91 | FNTA (0.59) | FNTAFNTBPGGT1BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986302-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | claimed |
| WO-1998054966-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | claimed |