SCHEMBL8107112

SCHEMBL8107112

CC(NC(=O)CC(=O)Nc1ccc(C(=N)N)cc1)c1ccc(OCC2C=COC2)c(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F7 P08709 20/20 0.49
F2 P00734 13/20 0.49
F10 P00742 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860870 0.85 F7 (0.52) F7F2F10
SCHEMBL860781 0.84 F7 (0.50) F7F2F10
SCHEMBL860354 0.83 F7 (0.49) F7F2F10
SCHEMBL860316 0.83 F7 (0.51) F7F2F10
SCHEMBL842037 0.82 F7 (0.50) F7F2F10
SCHEMBL841073 0.82 F7 (0.50) F7F2F10
SCHEMBL860311 0.81 F7 (0.49) F7F2F10
SCHEMBL860575 0.81 F7 (0.49) F7F2F10
SCHEMBL860532 0.81 F7 (0.49) F7F2F10
SCHEMBL860352 0.81 F7 (0.52) F7F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009007015-A1 MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY SANOFI-AVENTIS (FR) 2009-01-15 WO disclosed