Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | IGF2R | P11717 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132637 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL1958664 | 0.83 | RECQL (0.58) | EGFRRECQLSMN1; SMN2HIF1APDGFRB | |
| SCHEMBL1958666 | 0.83 | RECQL (0.58) | EGFRRECQLSMN1; SMN2HIF1APDGFRB | |
| SCHEMBL11822409 | 0.82 | MEN1 (0.67) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL11822393 | 0.82 | MEN1 (0.67) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL8130453 | 0.81 | MAPT (0.53) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL829253 | 0.80 | TUBB1 (0.68) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL829251 | 0.80 | TUBB1 (0.68) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL8134746 | 0.80 | MAPT (0.53) | MEN1KMT2AMAPTGAAEGFR | |
| SCHEMBL8135923 | 0.80 | MAPT (0.52) | MEN1KMT2AMAPTGAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645382-B1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |