Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 8/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567173 | 0.93 | NR1H2 (0.37) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL1241323 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL139880 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL1241324 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL1372634 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL20312947 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL142689 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL19964151 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL21286125 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 | |
| SCHEMBL2386707 | 0.88 | NR1H2 (0.42) | NR1H2ABCB1SRCALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015028409-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCING MEDICAMENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-03-05 | — | — | WO | disclosed |
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| US-5449672-A | Bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0544307-A1 | Alkylaminoakylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |