Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.58 |
| ▸ | BACE1 | P56817 | 7/20 | 0.56 |
| ▸ | ACHE | P22303 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107571 | 1.00 | BCHE (0.58) | BCHEBACE1ACHEDRD2DRD4 | |
| SCHEMBL668666 | 0.84 | SLC6A2 (0.68) | BCHEBACE1ACHEALDH1A1SLC6A2 | |
| SCHEMBL6662331 | 0.84 | BCHE (0.62) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL3708632 | 0.83 | BCHE (0.61) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL7514730 | 0.82 | BCHE (0.62) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL13766270 | 0.82 | BCHE (0.62) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL28511753 | 0.81 | BCHE (0.83) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL28496734 | 0.81 | BCHE (0.83) | BCHEBACE1ACHECYP1A2CYP3A4 | |
| SCHEMBL18105280 | 0.80 | BCHE (0.56) | BCHEACHECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL350928 | 0.79 | CYP1A2 (0.60) | BCHEBACE1ACHECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719772-B1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5726188-A | TREATING SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0719772-A1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |