SCHEMBL8107616

SCHEMBL8107616

Cl[SiH](Cl)CCC1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
SIGMAR1 Q99720 3/20 0.39
HPGD P15428 1/20 0.33
METAP1 P53582 1/20 0.32
CHRM5 P08912 2/20 0.32
ADRA2C P18825 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CEL P19835 2/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886447 0.74 CYP1A2 (0.42) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL1524766 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL2573209 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL6518887 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL11407095 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL60655 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL5617552 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL6524230 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL6077957 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5
SCHEMBL6520302 0.73 CYP1A2 (0.58) CYP1A2SIGMAR1HPGDMETAP1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444121-B Method for removing ethyl dichlorosilane impurities in dimethyl dichlorosilane 天津大学 2023-02-07 CN disclosed
CN-113444121-A Method for removing ethyl dichlorosilane impurities in dimethyl dichlorosilane 天津大学 2021-09-28 CN disclosed
US-8933259-B2 Continuous process for preparing SiOC-containing compounds WACKER CHEMIE AG (DE) 2015-01-13 US disclosed
US-20140005433-A1 CONTINUOUS PROCESS FOR PREPARING SiOC-CONTAINING COMPOUNDS WACKER CHEMIE AG (DE) 2014-01-02 US disclosed
US-6156918-A Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom WACKER-CHEMIE GMBH (DE) 2000-12-05 US disclosed
US-5663400-A Process for preparing alkylsilanes having bulky alkyl radicals WACKER-CHEMIE GMBH (DE) 1997-09-02 US disclosed
EP-0731104-B1 Process for the preparation of alkylsilanes containing bulky alkyl groups WACKER CHEMIE GMBH (DE) 1997-04-09 EP disclosed
EP-0731104-A1 Process for the preparation of alkylsilanes containing bulky alkyl groups Wacker-Chemie GmbH (DE) 1996-09-11 EP disclosed