SCHEMBL8107638

SCHEMBL8107638

CC(O)CC12CN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC(=O)N1CC1(CCN(c3ccncc3)CC1)O2

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6079662 0.90 F10 (0.68) F10
SCHEMBL6079429 0.89 F10 (0.61) F10
SCHEMBL2472196 0.88 F10 (0.60) F10
SCHEMBL6079052 0.87 F10 (0.60) F10
SCHEMBL6078035 0.87 F10 (0.59) F10
SCHEMBL6493104 0.87 F10 (0.59) F10
SCHEMBL6078920 0.87 F10 (0.59) F10
SCHEMBL6079359 0.85 F10 (0.60) F10
SCHEMBL7032394 0.85 F10 (0.58) F10
SCHEMBL6078530 0.85 F10 (0.57) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170877-B1 SUBSTITUTED (OXAZOLIDINON-5-YL-METHYL) -2-THIOPHENE-CARBOXAMIDES AND USE THEREOF IN THE FIELD OF BLOOD COAGULATION BAYER IP GMBH (DE) 2012-11-21 EP disclosed
WO-2008155069-A2 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-24 WO disclosed