⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394341 | 0.79 | — | — | |
| SCHEMBL3421681 | 0.79 | — | — | |
| SCHEMBL7246171 | 0.79 | — | — | |
| SCHEMBL1613037 | 0.75 | — | — | |
| SCHEMBL311281 | 0.75 | — | — | |
| SCHEMBL31160735 | 0.75 | — | — | |
| SCHEMBL20418620 | 0.75 | — | — | |
| SCHEMBL12743031 | 0.75 | — | — | |
| SCHEMBL14757558 | 0.75 | — | — | |
| SCHEMBL10161873 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101935317-B | Synthesizing method of 2-methyl-7-(substituted pyrimidine-4-amino)-4-(substituted piperazine-1-base) piperidine-1-base) isoindoline-1-ketone and intermediate thereof | WUXI APPTEC CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-101935317-A | Synthesizing method of 2-methyl-7-(substituted pyrimidine-4-amino)-4-(substituted piperazine-1-base) piperidine-1-base) isoindoline-1-ketone and intermediate thereof | YAOMING KANGDE NEW MEDICINE DEV SHANGHAI CO LTD | 2011-01-05 | — | — | CN | claimed |
| WO-2007126262-A1 | ANION RECEPTOR, AND ELECTROLYTE USING THE SAME | KYUNGWON ENTERPRISE CO., LTD. (KR) | 2007-11-08 | — | — | WO | claimed |
| EP-0644882-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025539-A1 | NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | claimed |
| CN-114423758-B | Antibacterial compounds | 爱尔兰詹森科学公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119954777-A | 2, 4-Diaminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-05-09 | — | — | CN | disclosed |
| US-20240199611-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-06-20 | — | — | US | disclosed |
| EP-4028399-B1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2024-02-14 | — | — | EP | disclosed |
| EP-4308239-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-01-24 | — | — | EP | disclosed |
| CN-117396475-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2024-01-12 | — | — | CN | disclosed |
| EP-4259637-A1 | H4 ANTAGONIST COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-10-18 | — | — | EP | disclosed |
| EP-0901476-A1 | ARYLOXY- AND ARYLTHIO-FUSED PYRIDINES AND PYRIMIDINES AND DERIVATIVES | Du Pont Pharmaceuticals Company (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997035846-A1 | ARYLOXY- AND ARYLTHIO-FUSED PYRIDINES AND PYRIMIDINES AND DERIVATIVES | DUPONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| EP-0644885-A1 | NOVEL BIOLOGICALLY ACTIVE EBURNAMENINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHETER GEDEON VEGYESZETI GYAR RT. (HU) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025550-A1 | NOVEL BIOLOGICALLY ACTIVE EBURNAMENINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHETER GEDEON VEGYÉSZETI GYÁR RT. (HU) | 1993-12-23 | — | — | WO | disclosed |
| US-4339453-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4083895-A | Modified block copolymers and process of preparing the same | MOBIL OIL CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-4082535-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-3954915-A | OIL ADDITIVES, HEAT AND OXIDATION RESISTANCE | MOBIL OIL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |