Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595803 | 1.00 | ABCB1 (0.44) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL9142600 | 0.89 | ABCB1 (0.48) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL7859579 | 0.85 | ABCB1 (0.42) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL9596796 | 0.85 | ABCB1 (0.42) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL8107606 | 0.85 | ABCB1 (0.42) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL8113850 | 0.81 | ABCB1 (0.36) | ABCB1ALDH1A1 | |
| SCHEMBL8098250 | 0.81 | DPP8 (0.38) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL8107543 | 0.81 | ABCB1 (0.40) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL10390670 | 0.81 | GAA (0.45) | ABCB1DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL10390672 | 0.81 | GAA (0.45) | ABCB1DPP8DPP9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |