Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24570 | 0.80 | — | — | |
| SCHEMBL477853 | 0.80 | — | — | |
| SCHEMBL477706 | 0.80 | — | — | |
| SCHEMBL29657081 | 0.77 | — | — | |
| Potassium SCHEMBL29657066 | 0.77 | — | — | |
| Lithium SCHEMBL29657113 | 0.77 | — | — | |
| SCHEMBL8108425 | 0.77 | TSHR (0.35) | TDP1TSHRALDH1A1MAPK1 | |
| Trifluoroethanol SCHEMBL10622289 | 0.74 | HTT (0.33) | — | |
| Trifluoroethanol SCHEMBL3396675 | 0.73 | — | — | |
| Trifluoroethanol SCHEMBL8952016 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022722-A | REGENERATION OF DENATURED POLYPEPTIDE; CONTACTING A DENATURED POLYPEPTIDE ADSORBED TO SOLID SUPPORT WITH TRIFLUOROETHANOL | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |