Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 7/20 | 0.64 |
| ▸ | PNP | P00491 | 8/20 | 0.41 |
| ▸ | AGL | P35573 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.38 |
| ▸ | GANC | Q8TET4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13538449 | 0.81 | MGAM (0.73) | MGAMAGLGAAGLAGBA2 | |
| Radicamine B SCHEMBL13848027 | 0.78 | MGAM (1.00) | MGAMPNPAGLGAAGLA | |
| Radicamine B SCHEMBL2439078 | 0.78 | MGAM (1.00) | MGAMPNPAGLGAAGLA | |
| SCHEMBL8124475 | 0.77 | MGAM (0.72) | MGAMPNPAGLGAAGLA | |
| SCHEMBL8122438 | 0.67 | MGAM (0.57) | MGAMAGLGAAGLAGBA2 | |
| Terephthalic Acid SCHEMBL9857246 | 0.64 | TSHR (0.80) | — | |
| Terephthalic Acid SCHEMBL1065024 | 0.64 | TSHR (0.92) | — | |
| Terephthalic Acid SCHEMBL1204011 | 0.64 | TSHR (0.92) | — | |
| Terephthalic Acid SCHEMBL11804308 | 0.62 | TSHR (0.67) | — | |
| Terephthalic Acid SCHEMBL319125 | 0.62 | TSHR (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121296-A | ADMINISTERING TO TREAT PARASITIC INFECTION OR DISEASE OR TO TREAT INFECTIONS AND DISEASES CAUSED BY CERTAIN BACTERIAL AND PLANT TOXINS; COMPOUNDS SUCH AS SALT OF 2-PHENYL-3,4-DIHYDROXY-5-HYDROXYMETHYL-PYRROLIDINE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-09-19 | — | — | US | disclosed |