Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217612 | 0.86 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL557685 | 0.81 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL191210 | 0.81 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL691398 | 0.78 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL30047710 | 0.78 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8109217 | 0.77 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL12825399 | 0.77 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL753276 | 0.77 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL22063717 | 0.76 | SMN1; SMN2 (1.00) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8219021 | 0.75 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | claimed |
| EP-0693061-B1 | FUNGICIDAL OXAZOLYL AND OXADIAZOLYL DERIVATIVES | ZENECA LTD (GB) | 2000-11-22 | — | — | EP | disclosed |
| US-5716974-A | TREATING FUNGAL PLANT DISEASES | ISAGRO S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| EP-0662477-A1 | Heterobicyclic compounds with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994022844-A1 | FUNGICIDAL OXAZOLYL AND OXADIAZOLYL DERIVATIVES | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |