Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.70 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.31 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.31 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649532 | 0.85 | ACACB (0.54) | ACACBMTNR1A | |
| SCHEMBL649531 | 0.85 | ACACB (0.54) | ACACBMTNR1A | |
| Hydrochloric Acid SCHEMBL8415498 | 0.84 | ACACB (0.53) | ACACBMTNR1A | |
| SCHEMBL647953 | 0.83 | ACACB (0.51) | ACACBACACAMTNR1AKCNH2 | |
| SCHEMBL2965199 | 0.83 | ACACB (0.51) | ACACBACACAMTNR1AKCNH2 | |
| SCHEMBL8103455 | 0.83 | ACACB (0.52) | ACACBMTNR1A | |
| SCHEMBL8109688 | 0.83 | ACACB (1.00) | ACACBACACAMTNR1A | |
| SCHEMBL8110393 | 0.80 | ACACB (0.48) | ACACBACACAMAOB | |
| SCHEMBL9352742 | 0.78 | SLC6A4 (0.43) | ACACBMTNR1A | |
| Hydrochloric Acid SCHEMBL9482107 | 0.77 | SLC6A4 (0.42) | ACACBMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986552-A1 | 5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055474-A1 | 5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 1998-12-10 | — | — | WO | disclosed |