Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.65 |
| ▸ | TACR1 | P25103 | 14/20 | 0.63 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955458 | 0.84 | TACR2 (0.90) | TACR2TACR1 | |
| SCHEMBL7951333 | 0.81 | TACR1 (0.55) | TACR2TACR1 | |
| SCHEMBL8113675 | 0.81 | TACR2 (0.58) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL7955332 | 0.80 | TACR1 (0.54) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL7955335 | 0.80 | TACR1 (0.54) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL7137386 | 0.78 | TACR2 (0.64) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL7137391 | 0.78 | TACR2 (0.64) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL6953772 | 0.78 | TACR2 (0.58) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL6957564 | 0.78 | TACR2 (0.54) | TACR2TACR1CCR5TACR3 | |
| SCHEMBL7137067 | 0.76 | TACR2 (0.70) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023285-A1 | AZETIDINYLPROPYLPIPERIDINE DERIVATIVES, INTERMEDIATES AND USE AS TACHYKININ ANTAGONISTS | Pfizer Limited (GB) | 2000-08-02 | — | — | EP | claimed |
| WO-1999001451-A1 | AZETIDINYLPROPYLPIPERIDINE DERIVATIVES, INTERMEDIATES AND USE AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1999-01-14 | — | — | WO | claimed |