Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.55 |
| ▸ | KLK1 | P06870 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026566 | 0.88 | F2 (0.63) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6635985 | 0.84 | ITK (0.43) | F2HDAC6 | |
| SCHEMBL6638105 | 0.79 | F2 (0.57) | F2KLK1KLK5F10PRSS1 | |
| SCHEMBL6779988 | 0.79 | F2 (0.71) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6633756 | 0.79 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6778628 | 0.76 | NQO2 (0.69) | F2KLK1KLK5F10PRSS1 | |
| SCHEMBL5970306 | 0.76 | F2 (0.70) | F2KLK1KLK5F10PRSS1 | |
| SCHEMBL6637006 | 0.75 | F2 (0.75) | F2KLK1KLK5F10PRSS1 | |
| SCHEMBL6633497 | 0.74 | KLK1 (0.65) | F2KLK1KLK5F10PRSS1 | |
| Hydrochloric Acid SCHEMBL8028962 | 0.74 | F2 (0.53) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |