SCHEMBL8109700

SCHEMBL8109700

C=S(=O)(NC(=O)CC(CCC)n1c(=O)n(Cc2csc3cccc(C)c23)c2ccccc21)c1cn(C)c(C)n1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 20/20 0.46
CTSG P08311 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2308871 0.93 CMA1 (0.47) CMA1CTSG
SCHEMBL2315816 0.85 CMA1 (0.47) CMA1CTSG
SCHEMBL2309067 0.85 CMA1 (0.53) CMA1CTSG
SCHEMBL2311463 0.84 CMA1 (0.56) CMA1CTSG
SCHEMBL2309104 0.83 CMA1 (0.53) CMA1CTSG
SCHEMBL2310573 0.83 CMA1 (0.47) CMA1CTSG
SCHEMBL2308341 0.82 CMA1 (0.49) CMA1CTSG
SCHEMBL2314325 0.80 CMA1 (0.48) CMA1CTSG
SCHEMBL2311525 0.80 CMA1 (0.48) CMA1CTSG
SCHEMBL2311849 0.80 CMA1 (0.46) CMA1CTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008147697-A1 BENZIMIDAZOLONE CHYMASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-12-04 WO disclosed