SCHEMBL8109705

SCHEMBL8109705

CCNCCNc1cccc2c1CN([C@H](CCCNC)c1ccc(OC)c(OC)c1)C2=O

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 15/20 0.52
TNF P01375 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115919 0.85 UTS2R (0.47) UTS2RTNF
SCHEMBL2345910 0.79 UTS2R (0.76) UTS2R
SCHEMBL2579623 0.79 UTS2R (0.67) UTS2R
SCHEMBL2345723 0.79 UTS2R (0.80) UTS2R
SCHEMBL3630717 0.78 UTS2R (0.66) UTS2R
SCHEMBL2582937 0.78 UTS2R (0.58) UTS2R
SCHEMBL2579249 0.78 UTS2R (0.74) UTS2R
SCHEMBL3634258 0.76 UTS2R (0.68) UTS2R
SCHEMBL3636429 0.75 UTS2R (0.68) UTS2R
SCHEMBL2345903 0.73 UTS2R (0.75) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153902-A2 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-12-18 WO disclosed