Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43742 | 0.87 | KMT2A (0.61) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL1603335 | 0.85 | PRSS1 (0.56) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL30593894 | 0.85 | KMT2A (0.59) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2002135 | 0.83 | PRSS1 (0.54) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL3441517 | 0.83 | PRSS1 (0.50) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| Iodide SCHEMBL10492687 | 0.83 | PRSS1 (0.54) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL43233 | 0.83 | PRSS1 (0.67) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL241908 | 0.83 | CYP19A1 (0.52) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL44568 | 0.83 | PRSS1 (0.62) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL27607807 | 0.82 | PRSS1 (0.46) | PRSS1PRSS2PRSS3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054867-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999036406-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 1999-07-22 | — | — | WO | disclosed |