Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 9/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984609 | 0.81 | TOP2A (0.74) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL9301385 | 0.76 | TOP2A (0.69) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL7239785 | 0.74 | TOP2A (0.66) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL9300052 | 0.74 | TOP2A (0.73) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL9300625 | 0.73 | TOP2A (0.62) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL14114226 | 0.73 | TOP2A (0.71) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9299913 | 0.72 | TOP2A (0.60) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL9299690 | 0.72 | TOP2A (0.73) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL7239792 | 0.72 | TOP2A (0.66) | TOP2ATOP2BHDAC4HDAC7HDAC6 | |
| SCHEMBL3983034 | 0.72 | TOP2A (0.77) | TOP2ATOP2BHDAC4HDAC7HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062207-A1 | 9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000037447-A1 | 9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-06-29 | — | — | WO | disclosed |