SCHEMBL8109982

SCHEMBL8109982

Cc1cc(C)c(C)cc1C.Cc1cc(C)c(C)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
CYP3A4 P08684 4/20 0.57
MAPK1 P28482 2/20 0.57
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 3/20 0.39
HPGD P15428 2/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
ACHE P22303 3/20 0.39
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
NQO2 P16083 1/20 0.37
NOS3 P29474 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39444 1.00 TSHR (0.57) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL30336851 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL28508031 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL27832465 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL31498545 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL25403085 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL5180999 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
SCHEMBL28708734 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
Bromide SCHEMBL29020310 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E
Methane SCHEMBL27933338 0.94 TSHR (0.53) TSHRCYP3A4MAPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1926083-B Manufacturing method of optical activity alcohol KANTO KAGAKU 2010-12-08 CN disclosed
CN-1926083-A Manufacturing method of optical activity alcohol NAGOYA IND SCIENCE RES INST (JP) 2007-03-07 CN disclosed
US-6156949-A Selective pseudocumene production by xylene methylation MOBIL OIL CORPORATION (US) 2000-12-05 US disclosed
EP-0744214-B1 Supported catalyst for oxidation reactions in the gas phase CONSORTIUM ELEKTROCHEM IND (DE) 1999-07-14 EP disclosed
US-5792719-A INERT SUPPORT BODY SURFACE COATED WITH NONCALCINED MIXTURE OF TITANIUM AND/OR ZIRCONIUM OXIDES, AND VANADIUM OXIDES, AND SILICON CARBIDE WHICH IS USED TO REPLACE SOME TITANIUM OXIDE; LOW HOT SPOT TEMPERATURE AT HIGH LOADINGS CONSORTIUM FUR ELEKTROCHENISCHE INDUSTRIE GMBH (DE) 1998-08-11 US disclosed
US-5691429-A POLYALKOXYBENZENES SHELL OIL COMPANY (US) 1997-11-25 US disclosed
EP-0744214-A1 Supported catalyst for oxydation reactions in the gaz phase Consortium für elektrochemische Industrie GmbH (DE) 1996-11-27 EP disclosed
US-5216152-A To yield hexamethyleneimine, hexamethylenediamine, and n-/6-aminohexyl/hexamethyleneimine E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-01 US disclosed
EP-0330195-B1 PROCESS FOR PRODUCING PYROMELLITIC DIANHYDRIDE AND CATALYST USED IN SAID PROCESS KAWASAKI STEEL CORPORATION (JP) 1993-05-12 EP disclosed
US-5001100-A Catalyst used in a process for producing pyromellitic dianhydride KAWASAKI STEEL CORPORATION (JP) 1991-03-19 US disclosed
US-4925957-A CATALYTIC OXIDATION OF DURENE KAWASAKI STEEL CORP. (JP) 1990-05-15 US disclosed
US-4347397-A ISOMERIZATION TO 1,2,3,4- AND 1,2,3,5- TETRAMETHYLBENZENES; ACID CATALYSTS MOBIL OIL CORPORATION (US) 1982-08-31 US disclosed
US-4228302-A Process for preparing a methyl-substituted benzaldehyde E. I. DUPONT DE NEMOURS AND COMPANY (US) 1980-10-14 US disclosed