Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 20/20 | 0.68 |
| ▸ | CTSG | P08311 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311480 | 0.97 | CMA1 (0.68) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL8101232 | 0.95 | CMA1 (0.69) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2309466 | 0.91 | CMA1 (0.70) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2311128 | 0.90 | CMA1 (0.73) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2309191 | 0.90 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2314595 | 0.90 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2309639 | 0.90 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL8103715 | 0.90 | CMA1 (0.61) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL8101233 | 0.90 | CMA1 (0.61) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL8118952 | 0.89 | CMA1 (0.66) | CMA1CTSGHTR1DOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147697-A1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |