SCHEMBL8110795

SCHEMBL8110795

O=S=S1CCCc2cc(-c3cc(-c4ccncc4)c(-c4cccc(Cl)c4)[nH]3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 7/20 0.54
MAPK14 Q16539 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115517 0.89 GCGR (0.47) GCGRMAPK14
SCHEMBL8116126 0.87 GCGR (0.43) GCGRMAPK14
SCHEMBL8111413 0.85 MAPK14 (0.56) GCGRMAPK14
SCHEMBL8110230 0.84 MAPK14 (0.44) GCGRMAPK14
SCHEMBL8110792 0.79 GCGR (0.57) GCGRMAPK14
SCHEMBL8111026 0.76 GCGR (0.59) GCGRMAPK14
SCHEMBL8117401 0.75 GCGR (0.57) GCGRMAPK14
SCHEMBL8322140 0.69 MAPK14 (0.68) GCGRMAPK14
SCHEMBL8101819 0.68 MAPK14 (0.53) GCGRMAPK14
SCHEMBL8115515 0.67 GCGR (0.49) GCGRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1031572-A1 PYRIDYLPYRROLE DERIVATIVES Sankyo Company Limited (JP) 2000-08-30 EP disclosed