SCHEMBL81110

SCHEMBL81110

BS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16005527 0.87
SCHEMBL13410315 0.71
SCHEMBL3431209 0.58
SCHEMBL29570578 0.58
SCHEMBL3507359 0.41
SCHEMBL2479202 0.41
SCHEMBL3411159 0.41
SCHEMBL3760827 0.41
SCHEMBL333801 0.41
SCHEMBL4770192 0.41

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1072 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107567471-A Process for preparing a composition comprising a first polyolefin block and a second polymer block and product obtained from said process SABIC环球技术有限责任公司 2018-01-09 CN claimed
CN-107531829-A For the product for preparing the method for the block copolymer comprising the first polyolefin block and second polymer block and being obtained from methods described SABIC环球技术有限责任公司 2018-01-02 CN claimed
EP-3040140-A1 METHOD OF PREPARING NANO-COPPER POWDER AND NANO-COPPER POWDER PREPARED WITH THE SAME Institute Of Chemistry, Chinese Academy Of Sciences (CN) 2016-07-06 EP claimed
US-20160184900-A1 METHOD FOR PREPARING NANO-COPPER POWDER INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-06-30 US claimed
EP-2331545-B1 IMPROVED PROCESS FOR PREPARATION OF (2R)-4-OXO-4-[3- (TRIFLUOROMETHYL)-5,6-DIHYDRO [1,2,4]-TRIAZOLO[4,3-A]PYRAZIN- 7(8H)-YL]-L-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE&amp;NEW IMPURITIES IN PREPARATION THEREOF CADILA HEALTHCARE LTD (IN) 2013-10-02 EP claimed
US-8476437-B2 Process for preparation of (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl]-l-(2,4,5-trifluorophenyl)butan-2-amine and new impurities in preparation thereof CADILA HEALTHCARE LIMITED (IN) 2013-07-02 US claimed
US-20110213149-A1 PROCESS FOR PREPARATION OF (2R)-4-OXO-4-[3- (TRIFLUOROMETHYL)-5,6-DIHYDRO [1,2,4]-TRIAZOLO[4,3-A]PYRAZIN- 7(8H)-YL]-L-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE &amp; NEW IMPURITIES IN PREPARATION THEREOF CADILA HEALTHCARE LIMITED (IN) 2011-09-01 US claimed
EP-2331545-A2 IMPROVED PROCESS FOR PREPARATION OF (2R)-4-OXO-4-[3- (TRIFLUOROMETHYL)-5,6-DIHYDRO [1,2,4]-TRIAZOLO[4,3-A]PYRAZIN- 7(8H)-YL]-L-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE&amp;NEW IMPURITIES IN PREPARATION THEREOF Cadila Healthcare Limited (IN) 2011-06-15 EP claimed
WO-2010032264-A2 IMPROVED PROCESS FOR PREPARATION OF (2R)-4-OXO-4-[3- (TRIFLUOROMETHYL)-5,6-DIHYDRO [1,2,4]-TRIAZOLO[4,3-A]PYRAZIN- 7(8H)-YL]-L-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE &amp; NEW IMPURITIES IN PREPARATION THEREOF CADILA HEALTHCARE LIMITED (IN) 2010-03-25 WO claimed
EP-1694683-A4 SYNTHETIC PROCESS BRISTOL MYERS SQUIBB CO (US) 2009-06-24 EP claimed
US-20080166361-A1 Neutron Capture Therapy PATEL BIPIN CHANDRA MUJIBHIA 2008-07-10 US claimed
EP-1694683-A2 SYNTHETIC PROCESS Bristol-Myers Squibb Company (US) 2006-08-30 EP claimed
US-20050209454-A1 Synthetic process BRISTOL-MYERS SQUIBB COMPANY 2005-09-22 US claimed
WO-2005058245-A2 SYNTHETIC PROCESS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-06-30 WO claimed
US-20040180057-A1 Neutron capture therapy PSIMEI PHARMACEUTICALS PLE 2004-09-16 US claimed
WO-2002096437-A1 NEUTRON CAPTURE THERAPY PSIMEI PHARMACEUTICALS PLC (GB) 2002-12-05 WO claimed
CN-1169416-A Method for synthesizing sex information hormone of bollworm BEIJING POLYTECHNIQUE UNIV (CN) 1998-01-07 CN claimed
US-5653957-A ANTITUMOR AGENTS ASSOCIATED UNIVERSITIES, INC. (US) 1997-08-05 US claimed
US-5612017-A BORON CAGE COMPOUNDS ASSOCIATED UNIVERSITIES, INC. (US) 1997-03-18 US claimed
US-5455022-A Provide means for directly quantifying boron concentrations in tissues, thereby permitting rapid enhanced targeting ASSOCIATED UNIVERSITIES, INC. (US) 1995-10-03 US claimed