Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.46 |
| ▸ | GCGR | P47871 | 9/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115541 | 0.94 | MAPK14 (0.47) | MAPK14GCGRMAPK13RAF1MAPK9 | |
| SCHEMBL8110021 | 0.93 | MAPK14 (0.46) | MAPK14GCGRMAPK13RAF1MAPK9 | |
| SCHEMBL7866589 | 0.90 | MAPK14 (0.59) | MAPK14GCGRMAPK13RAF1MAPK9 | |
| SCHEMBL8111525 | 0.88 | GCGR (0.49) | MAPK14GCGR | |
| SCHEMBL8117401 | 0.86 | GCGR (0.57) | MAPK14GCGR | |
| SCHEMBL8110130 | 0.83 | MAPK14 (0.62) | MAPK14GCGRMAPK13RAF1MAPK9 | |
| SCHEMBL8102629 | 0.78 | GCGR (0.47) | MAPK14GCGR | |
| SCHEMBL8116122 | 0.76 | GCGR (0.46) | MAPK14GCGR | |
| SCHEMBL8109976 | 0.75 | GCGR (0.49) | MAPK14GCGR | |
| SCHEMBL8116126 | 0.74 | GCGR (0.43) | MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |