Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471410 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL24729036 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A4CDK4CCND1HTR2A | |
| SCHEMBL599150 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A4CDK4CCND1HTR2A | |
| SCHEMBL16984737 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL18258618 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL21119323 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4 | |
| SCHEMBL20037238 | 0.76 | SLC6A2 (0.57) | SLC6A2SLC6A4CDK4CCND1HTR2A | |
| SCHEMBL20379514 | 0.74 | SLC6A2 (0.46) | SLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL598296 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL29591657 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |