SCHEMBL8112686

SCHEMBL8112686

NCC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC(=O)N1CC1CCN(c2ccncc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.55
TPSAB1 Q15661 1/20 0.44
HTR7 P34969 1/20 0.43
HTR6 P50406 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8125937 0.96 F10 (0.53) F10
SCHEMBL8123599 0.92 F10 (0.56) F10
SCHEMBL8111924 0.90 F10 (0.52) F10
SCHEMBL8120894 0.90 F10 (0.52) F10
SCHEMBL8111927 0.90 F10 (0.52) F10
SCHEMBL8121151 0.90 F10 (0.52) F10
SCHEMBL8126491 0.90 F10 (0.51) F10TPSAB1HTR7HTR6
SCHEMBL8121988 0.90 F10 (0.51) F10
SCHEMBL8121987 0.90 F10 (0.54) F10
SCHEMBL8137280 0.89 F10 (0.54) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048652-A1 AROMATIC COMPOUNDS HAVING CYCLIC AMINO OR SALTS THEREOF MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP claimed
EP-1048652-A1 AROMATIC COMPOUNDS HAVING CYCLIC AMINO OR SALTS THEREOF MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed