Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118867 | 0.92 | PRSS1 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8112435 | 0.89 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8118698 | 0.87 | F2 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8113077 | 0.87 | F2 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8119731 | 0.85 | F10 (0.62) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8119899 | 0.85 | F10 (0.44) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8104721 | 0.85 | F10 (0.69) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8104157 | 0.85 | PRSS1 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8118722 | 0.84 | F10 (0.60) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8115002 | 0.82 | POLB (0.45) | LMNAMAPTRAB9ATHRBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |