Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 5/20 | 0.51 |
| ▸ | CCR8 | P51685 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139256 | 0.90 | CCR1 (0.61) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL29535245 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL29506435 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL29506438 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL9935892 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL29589086 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL15549459 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL30839623 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL28561521 | 0.88 | CCR1 (0.59) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| Phenanthroline SCHEMBL8357993 | 0.85 | CCR1 (0.57) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546563-B1 | Complex crystal | TOYOTA MOTOR CO LTD (JP) | 2000-11-08 | — | — | EP | claimed |
| EP-0546563-A2 | Complex crystal | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0546563-B1 | Complex crystal | TOYOTA MOTOR CO LTD (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5710273-A | AND AN ANION OF TRIIODINE AND AN ACID, LIGHT ADJUSTING COMPONENT FOR AUTOMOBILE WINDSHIELDS | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5646284-A | AUTOMOBILE WINDSHIELDS THAT SCREEN LIGHT | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0546563-A2 | Complex crystal | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |