SCHEMBL8114493

SCHEMBL8114493

CCC(CO)(CO)CO.CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
THRB P10828 1/20 0.59
HTT P42858 1/20 0.59
KMT2A Q03164 1/20 0.59
MAPT P10636 1/20 0.59
TSHR P16473 1/20 0.48
USP2 O75604 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 1/20 0.46
LPAR3 Q9UBY5 3/20 0.42
LPAR1 Q92633 2/20 0.42
LPAR2 Q9HBW0 2/20 0.42
GBA2 Q9HCG7 9/20 0.41
GBA1 P04062 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7092144 1.00 MEN1 (0.59) MEN1THRBHTTKMT2AMAPT
SCHEMBL20854593 1.00 MEN1 (0.59) MEN1THRBHTTKMT2AMAPT
SCHEMBL1072080 0.98 MEN1 (0.56) MEN1THRBHTTKMT2AMAPT
SCHEMBL1115457 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL4307710 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL8483594 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL8482624 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL18954849 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL8611137 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT
SCHEMBL8481402 0.91 HTT (0.64) MEN1THRBHTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060740-A1 Aqueous pearlescent concentrate Cognis Deutschland GmbH (DE) 2000-12-20 EP disclosed