Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | PDE8B | O95263 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490830 | 0.91 | TLR7 (0.41) | TLR7TLR8KDM4EHPGDACHE | |
| SCHEMBL5124071 | 0.86 | TLR7 (0.36) | TLR7TLR8KDM4EHPGDALDH1A1 | |
| SCHEMBL8113805 | 0.86 | TLR7 (0.39) | TLR7TLR8KDM4EHPGDALDH1A1 | |
| SCHEMBL8113959 | 0.86 | TLR7 (0.45) | TLR7TLR8PDE8BKDM4EHPGD | |
| SCHEMBL1490647 | 0.85 | TLR7 (0.38) | TLR7TLR8KDM4EHSD17B10HPGD | |
| SCHEMBL1490659 | 0.85 | TLR7 (0.37) | TLR7TLR8HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1490823 | 0.84 | TLR7 (0.38) | TLR7TLR8KDM4EHPGDMAPK1 | |
| SCHEMBL4088138 | 0.84 | TLR7 (0.37) | TLR7TLR8KDM4EHSD17B10HPGD | |
| SCHEMBL13888876 | 0.83 | TLR7 (0.36) | TLR7 | |
| Hydrochloric Acid SCHEMBL4523887 | 0.82 | TLR7 (0.36) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | claimed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | claimed |
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5886006-A | VIRICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5648516-A | INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5627281-A | CHEMCAL INTERMEDIATES FOR VIRICIDES BY INDUCING SYNTHESIS OF INTERFERONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5444065-A | Viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | disclosed |