SCHEMBL8115352

SCHEMBL8115352

CCCCCCCN1C(=O)CC(=O)N(CCCCCCC)C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
USP2 O75604 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 2/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
MGLL Q99685 5/20 0.53
PTGS1 P23219 3/20 0.53
PTGS2 P35354 3/20 0.53
FAAH O00519 3/20 0.53
GAA P10253 2/20 0.46
ALDH1A1 P00352 1/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP19A1 P11511 3/20 0.42
GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580230 1.00 MAPT (0.54) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL8121430 1.00 MAPT (0.54) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL4578069 1.00 MAPT (0.54) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL5450752 1.00 MAPT (0.54) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL5014433 0.98 MAPT (0.51) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL12101788 0.96 MAPT (0.50) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL10972869 0.94 MAPT (0.50) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL10702779 0.94 MAPT (0.50) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL3420629 0.91 MAPT (0.49) MAPTMEN1USP2KMT2AKDM4E
SCHEMBL8338673 0.91 MAPT (0.47) MAPTMEN1USP2KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed