Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 14/20 | 0.59 |
| ▸ | EDNRB | P24530 | 12/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332607 | 0.94 | EDNRA (0.68) | EDNRAEDNRBAGTR1LMNATP53 | |
| SCHEMBL7335601 | 0.88 | EDNRA (0.52) | EDNRAEDNRBAGTR1LMNACYP1A2 | |
| SCHEMBL5494850 | 0.87 | EDNRA (0.65) | EDNRAEDNRBAGTR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5496424 | 0.86 | EDNRA (0.65) | EDNRAEDNRBAGTR1AGTR2 | |
| SCHEMBL5489155 | 0.85 | EDNRA (0.66) | EDNRAEDNRBAGTR1GAAAGTR2 | |
| SCHEMBL7330600 | 0.84 | EDNRA (0.77) | EDNRAEDNRBAGTR1AGTR2 | |
| SCHEMBL7335276 | 0.82 | EDNRA (0.73) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7339608 | 0.82 | EDNRA (0.69) | EDNRAEDNRBAGTR1TSHRSMN1; SMN2 | |
| SCHEMBL7329183 | 0.81 | EDNRA (0.86) | EDNRAEDNRBAGTR1AGTR2 | |
| SCHEMBL7333529 | 0.81 | EDNRA (0.76) | EDNRAEDNRBAGTR1SMN1; SMN2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617001-B1 | Phenoxyphenylacetic acid derivatives | MERCK & CO INC (US) | 2000-01-26 | — | — | EP | claimed |