Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13251238 | 0.94 | MAPT (0.58) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL2564281 | 0.89 | TDP1 (0.56) | MAPTL3MBTL1CRHBPCRHR2KCNH2 | |
| SCHEMBL10559291 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL10558691 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL9570637 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL10554981 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL5390369 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL10556391 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL9570561 | 0.87 | HRH3 (0.69) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL7805048 | 0.86 | MAPT (0.65) | MAPTL3MBTL1CRHBPCRHR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632031-B1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5496853-A | FOR TREATING HYPERCHOLESTEROLEMIA | TEIJIN LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0632031-A1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |