SCHEMBL811754

SCHEMBL811754

Fc1ccc(-c2ccc(F)cn2)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 10/20 0.47
CCR1 P32246 1/20 0.46
CCR5 P51681 1/20 0.46
CCR8 P51685 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
MAPT P10636 1/20 0.44
NPC1 O15118 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CYP1A2 P05177 1/20 0.41
TRPV3 Q8NET8 1/20 0.39
P4HA1 P13674 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
TGFBR1 P36897 2/20 0.38
MAPK14 Q16539 1/20 0.38
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
PTPN11 Q06124 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15624380 0.85 CCR1 (0.48) GRM5CCR1CCR5CCR8HDAC6
SCHEMBL23348866 0.84 GRM5 (0.44) GRM5MAPTNPC1RXFP1TRPV3
SCHEMBL13830491 0.84 NPC1 (0.41) GRM5CCR1CCR5CCR8HDAC6
SCHEMBL29901522 0.83 KDM4E (0.61) CCR1CCR5CCR8MAPTNPC1
SCHEMBL19815716 0.82 GRM5 (0.38) GRM5CCR1CCR5CCR8HDAC6
SCHEMBL29391733 0.82 MAPT (0.46) GRM5MAPTCYP1A2TGFBR1MAPK14
SCHEMBL882102 0.82 FEN1 (0.46) MAPT
SCHEMBL15604653 0.80 MAPT (0.39) GRM5CCR1CCR5CCR8HDAC6
SCHEMBL5226125 0.80 MAPT (0.42) GRM5CCR1CCR5CCR8HDAC6
SCHEMBL19072737 0.80 GRM5 (0.47) GRM5NPC1RXFP1CYP1A2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
US-11890604-B2 Composite catalyst for carbon dioxide reduction and method of fabricating of the same KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2024-02-06 US disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed
US-20210220809-A1 COMPOSITE CATALYST FOR CARBON DIOXIDE REDUCTION AND METHOD OF FABRICATING OF THE SAME KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2021-07-22 US disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
WO-2014044685-A1 FLUORINATED COBALT REDOX MEDIATOR, METHOD FOR PRODUCING THE SAME, AND ITS USE IN DYE-SENSITIZED SOLAR CELL SOLVAY SA (BE) 2014-03-27 WO disclosed
EP-2711360-A1 Fluorinated cobalt redox mediator, method for producing the same, and its use in dye-sensitized solar cell Solvay SA (BE) 2014-03-26 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110256790-A1 THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL SAINT-GOBAIN ISOVER (FR) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 GRM5 4430/4885CCR1 286/4885CCR5 1341/4885
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 GRM5 2779/4885CCR1 118/4885CCR5 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.