Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 4/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139526 | 0.98 | SCN2A (0.50) | SCN2ANPY5RCNR2CNR1MAP4K4 | |
| SCHEMBL7142302 | 0.95 | SCN2A (0.52) | SCN2ANPY5RCNR2CNR1MAP4K4 | |
| SCHEMBL7143478 | 0.91 | KCNH2 (0.49) | SCN2ACNR2CNR1MAP4K4PARP1 | |
| SCHEMBL8190593 | 0.90 | KCNH2 (0.48) | SCN2ACNR2CNR1MAP4K4PARP1 | |
| SCHEMBL8119014 | 0.88 | KCNH2 (0.51) | CNR2CNR1MAP4K4PARP1HPGDS | |
| SCHEMBL7138368 | 0.86 | CNR2 (0.47) | SCN2ACNR2CNR1MAP4K4HPGDS | |
| SCHEMBL8118669 | 0.84 | KCNH2 (0.46) | CNR2CNR1MAP4K4PARP1HPGDS | |
| SCHEMBL7142374 | 0.81 | SCN2A (0.58) | SCN2ANPY5RCNR2CNR1PRMT6 | |
| SCHEMBL7145532 | 0.79 | SCN2A (0.53) | SCN2ANPY5RCNR2CNR1MAP4K4 | |
| SCHEMBL7140240 | 0.78 | SCN2A (0.42) | SCN2ANPY5RCNR2CNR1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996443-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 2000-05-03 | — | — | EP | claimed |
| WO-1999001128-A1 | CERTAIN DIARYLIMIDAZOLE DERIVATIVES; A NEW CLASS OF NPY SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |