Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.71 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811919 | 0.93 | S1PR1 (0.84) | S1PR1S1PR3 | |
| SCHEMBL566670 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL565149 | 0.84 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL566505 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL566455 | 0.79 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL566078 | 0.77 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL565947 | 0.75 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL10139282 | 0.72 | S1PR1 (0.81) | S1PR1S1PR3 | |
| SCHEMBL566013 | 0.71 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL1964998 | 0.71 | S1PR1 (0.66) | S1PR1S1PR3MAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | claimed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | claimed |