⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550163 | 0.77 | — | — | |
| SCHEMBL8167028 | 0.72 | — | — | |
| SCHEMBL11560484 | 0.72 | — | — | |
| SCHEMBL11565210 | 0.72 | — | — | |
| SCHEMBL11443689 | 0.72 | — | — | |
| SCHEMBL46521 | 0.72 | — | — | |
| SCHEMBL19266226 | 0.65 | — | — | |
| SCHEMBL5150841 | 0.65 | — | — | |
| SCHEMBL5497435 | 0.61 | — | — | |
| SCHEMBL5157691 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588917-B1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2000-11-08 | — | — | EP | disclosed |
| US-5409946-A | Antiepileptic agent | ABBOTT LABORATORIES (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0588917-A4 | — | — | 1994-04-13 | — | — | EP | disclosed |
| EP-0588917-A1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992021339-A1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |