Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 14/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.48 |
| ▸ | NPY4R | P50391 | 3/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126824 | 0.91 | NPY1R (0.63) | NPY1RNPY5RNPY4RNPY2RNPFFR1 | |
| SCHEMBL8126339 | 0.90 | NPY1R (0.52) | NPY1RNPY5RNPY4RNPY2RNPFFR1 | |
| SCHEMBL8122091 | 0.89 | NPY1R (0.51) | NPY1RNPY5RNPY4RNPY2RNPFFR1 | |
| SCHEMBL8112974 | 0.89 | NPY1R (0.51) | NPY1RNPY5RNPY4RNPY2RNPFFR1 | |
| SCHEMBL8121483 | 0.88 | NPY1R (0.60) | NPY1RNPY5RNPY4RNPY2RNPFFR1 | |
| SCHEMBL7037325 | 0.88 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY4RNPY2R | |
| SCHEMBL7042397 | 0.88 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY4RNPY2R | |
| SCHEMBL7042405 | 0.88 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY4RNPY2R | |
| SCHEMBL8121280 | 0.88 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY4RNPY2R | |
| SCHEMBL7037336 | 0.88 | NPY1R (0.51) | NPY1RCNR1NPY5RNPY4RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |