Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 12/20 | 0.86 |
| ▸ | CTSG | P08311 | 3/20 | 0.65 |
| ▸ | CDK1 | P06493 | 6/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.38 |
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314701 | 0.93 | CMA1 (1.00) | CMA1CTSGCDK1CCNB2CCNB1 | |
| SCHEMBL12431643 | 0.83 | CMA1 (0.82) | CMA1CTSGCDK1CCNB2CCNB1 | |
| SCHEMBL2313030 | 0.82 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2309855 | 0.79 | CMA1 (1.00) | CMA1CTSGCDK1CCNB2CCNB1 | |
| SCHEMBL8122295 | 0.78 | CMA1 (0.75) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2314943 | 0.75 | CMA1 (0.83) | CMA1CTSGCDK1CCNB2CCNB1 | |
| SCHEMBL12432102 | 0.73 | CMA1 (0.79) | CMA1CTSG | |
| SCHEMBL2311999 | 0.71 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL2312058 | 0.70 | CMA1 (0.69) | CMA1CTSG | |
| SCHEMBL2315425 | 0.69 | CMA1 (1.00) | CMA1CTSGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147697-A1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |