Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769204 | 1.00 | PREP (0.57) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL29847526 | 0.91 | SMN1; SMN2 (0.58) | PREPSMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL29107116 | 0.87 | DPP4 (0.45) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3049973 | 0.84 | PREP (0.58) | PREPSMN1; SMN2CYP2C19ACE2NPC1 | |
| SCHEMBL4344988 | 0.84 | KDM1A (0.54) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3076586 | 0.84 | PREP (0.55) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3088051 | 0.84 | PREP (0.55) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3088055 | 0.84 | PREP (0.55) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3076595 | 0.84 | PREP (0.55) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 | |
| SCHEMBL3076590 | 0.84 | PREP (0.55) | PREPSMN1; SMN2CYP2C19KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2007009716-A1 | PREPARATION OF TERAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | PREP 4006/4885SMN1; SMN2 3982/4885CYP2C19 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.