Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.67 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.67 |
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932555 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL11322082 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL28373061 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL2829024 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL10943900 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL1573968 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL5473083 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL8936597 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL11095674 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL9771499 | 0.85 | NR5A1 (0.79) | TP53TSHRPLA2G4BNR5A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632031-B1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5496853-A | FOR TREATING HYPERCHOLESTEROLEMIA | TEIJIN LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0632031-A1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |