Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
| ▸ | NPY4R | P50391 | 3/20 | 0.54 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126824 | 0.94 | NPY1R (0.63) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8120506 | 0.91 | NPY1R (0.63) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8124246 | 0.90 | NPY1R (0.72) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8528488 | 0.90 | NPY1R (0.62) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8111886 | 0.90 | NPY1R (0.62) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8127052 | 0.89 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8126762 | 0.89 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7042824 | 0.89 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8125834 | 0.89 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8119572 | 0.89 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |